Epidemiology and aetiologies of hypopituitarism

Brue, Thierry (2013) Epidemiology and aetiologies of hypopituitarism. Reviews in endocrinology and metabolism, 1 (2). pp. 55-56. ISSN 2282-8362

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Anterior Pituitary Hormone Deficiencies may be due to any lesion in this anatomical region, most commonly benign tumors like pituitary adenomas or craniopharyngiomas, and to surgical or radiation-based treatments of these tumors. Less frequently, cranial traumas, inflammatory or autoimmune processes like lymphocytic hypophysitis or genetic defects may cause pituitary deficits. The resulting pituitary hormone deficiencies may lead to severe clinical consequences with significant morbidity and often increased mortality despite recent therapeutic improvements. The large observational studies launched for the follow-up of patients treated by growth hormone have provided valuable epidemiological data. In recent years, new aetiologies of acquired hypopituitarism have been reported such as hypophysitis following targeted anticancer immune therapies. Hypopituitarism however remains predominantly a consequence of benign pituitary tumors and of their treatments.

Item Type: Article
Uncontrolled Keywords: Hypopituitarism, anterior pituitary hormone deficit, combined pituitary hormone deficiency, growth hormone, causes
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.4 Malattie del sistema emopoietico, linfatico, ghiandolare; Malattie del sistema endocrino
Depositing User: Matteo Viola
Date Deposited: 17 Jun 2014 13:09
Last Modified: 17 Jun 2014 13:09
URI: http://eprints.bice.rm.cnr.it/id/eprint/8551

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