Sellar metastases

Bolanowski, Marek (2013) Sellar metastases. Reviews in endocrinology and metabolism, 1 (2). pp. 78-79. ISSN 2282-8362

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Tumor metastases within the sellar region are uncommon, accounting for up to 5% of all malignant lesions, and they can mimic pituitary tumor. These metastases are usually observed in older patients, with advanced and generalized neoplastic disease, but also can be the first manifestation of the cancer. Possible hormonal disturbances are diabetes insipidus, hypopituitarism, isolated hormone deficiency and mild hyperprolactinemia. Mass effects, visual field defects, and headaches occur, too. The most common origin of the pituitary metastases are breast and lung cancer, then colon, prostate, pancreas, thyroid, hematologic disorders and other neoplasms. The treatment options include neurosurgical resection, irradiation and chemotherapy. In some cases transsphenoidal surgery might be helpful for the proper histological diagnosis. The prognosis is poor and is related to the response to the therapy of primary focus. Cases of lung tumor metastatic to the pituitary and lymphoma infiltrating the hypothalamus will be presented and discussed.

Item Type: Article
Uncontrolled Keywords: Sellar metastases, hypopituitarism, cancer
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.4 Malattie del sistema emopoietico, linfatico, ghiandolare; Malattie del sistema endocrino
Depositing User: Matteo Viola
Date Deposited: 17 Jun 2014 13:23
Last Modified: 17 Jun 2014 13:23

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