Quantitative ultrasound of bone: calcaneus

Cepollaro, Chiara (2005) Quantitative ultrasound of bone: calcaneus. Clinical cases in mineral and bone metabolism, 2 (2). pp. 127-132. ISSN 1971-3266

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In the last 25 years, several non-invasive techniques based on the attenuation of ionising radiation have been developed to quantify bone mineral density in the axial and peripheral skeleton. They represent valid methods for determination of BMD and explain about 60-80% of the variation in bone strength. However, they provide only limited information on bone structure and on bone material properties. Quantitative ultrasound (QUS) methods have been introduced for the assessment of skeletal status in osteoporosis; the physical interaction of ultrasound and bone is complex, and not completely understood; however, it is considered that QUS provides information both on bone mass and structure. QUS, because of the lack of ionising radiation, relative portability of the equipment, ease of use, and low cost, has seen marked success around the world, though it has been approved only in 1999 by FDA for clinical use in USA. The relative contribution to bone assessment of both ultrasound and the current gold standard method for bone assessment, dual x-ray absorptiometry (DXA), is still to be determined; nevertheless, QUS has demonstrated that it is able to detect bone fragility as well as DXA. Further studies needed on the diagnosis of osteoporosis using ultrasound, because current diagnostic threshold designed by the World Health Organization, cannot be always applied to QUS parameters. A better option for QUS would be to report results in terms of fracture risk, keeping in mind that a risk estimate depends not only on QUS or DXA measurement, but also on clinical risk factors

Item Type: Article
Uncontrolled Keywords: Quantitative ultrasound, bone quality, speed of sound, broadband ultrasound attenuation
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User: Danilo Dezzi
Date Deposited: 24 Apr 2014 11:14
Last Modified: 24 Apr 2014 11:14
URI: http://eprints.bice.rm.cnr.it/id/eprint/8863

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