The treatment of chondral lesions of the knee with the microfracture technique and platelet-rich plasma

Manunta, Andrea F. and Manconi, Anna (2013) The treatment of chondral lesions of the knee with the microfracture technique and platelet-rich plasma. Joints, 1 (4). pp. 167-170. ISSN 2282-4324

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Purpose: to assess the efficacy of associating the microfracture technique with platelet-rich plasma (PRP) injections in the treatment of chondral lesions to promote acceleration and optimization of the healing process compared with the traditional microfracture approach. Methods: from September 2011 to August 2012, 20 patients (9 males and 11 females, aged 30-55 years) were treated. All presented with chondral lesions of the medial femoral condyle of the knee and a pain duration ranging from 8 to 12 months. The patients were randomized into two groups (A and B). Group A was treated with the microfracture technique and a total of three intra-articular injections of PRP. Group B was treated with microfractures alone. Clinical follow-up was performed at 3, 6 and 12 months after treatment. Clinical function was assessed on the basis of the International Knee Documentation Committee (IKDC) score. Pain was evaluated using a visual analogue scale (VAS). Results: the patients in group A had a mean baseline IKDC score of 31.2, which rose to 84.2 at 12 months. The IKDC scores in group B were at 30.1 at baseline and 81 at 12 months. Conclusions: the results of our study suggest that functional recovery and resolution of pain are obtained more quickly in PRP-treated patients. We also observed a better functional outcome in the patients treated with the combination of PRP and microfractures, even at 12 months, although the difference was not statistically significant. Level of evidence: level II, randomized clinical study.

Item Type: Article
Uncontrolled Keywords: Chondral lesions, cartilage regeneration, microfracture, platelet-rich plasma
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia > 617.4 Chirurgia secondo il Sistema e Regioni
Depositing User: Chiara D'Arpa
Date Deposited: 01 Sep 2014 15:16
Last Modified: 01 Sep 2014 15:16

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