The Achilles tendon: fundamental properties and mechanisms governing healing

Freedman, Benjamin R. and Gordon, Joshua A. and Soslowsky, Louis J. (2014) The Achilles tendon: fundamental properties and mechanisms governing healing. M.L.T.J. Muscles, Ligaments and Tendons Journal, 4 (2). pp. 245-255. ISSN 2240-4554

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This review highlights recent research on Achilles tendon healing, and comments on the current clinical controversy surrounding the diagnosis and treatment of injury. The processes of Achilles tendon healing, as demonstrated through changes in its structure, composition, and biomechanics, are reviewed. Finally, a review of tendon developmental biology and mechano transductive pathways is completed to recognize recent efforts to augment injured Achilles tendons, and to suggest potential future strategies for therapeutic intervention and functional tissue engineering. Despite an abundance of clinical evidence suggesting that current treatments and rehabilitation strategies for Achilles tendon ruptures are equivocal, significant questions remain to fully elucidate the basic science mechanisms governing Achilles tendon injury, healing, treatment, and rehabilitation.

Item Type: Article
Uncontrolled Keywords: biomechanics, foot and ankle, tendinopathy, Achilles tendon rupture, injury, developmental biology, tissue engineering
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia > 617.1 Ferite e lesioni
Depositing User: Chiara D'Arpa
Date Deposited: 20 May 2015 14:28
Last Modified: 20 May 2015 14:28

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