Freedman, Benjamin R. and Gordon, Joshua A. and Soslowsky, Louis J. (2014) The Achilles tendon: fundamental properties and mechanisms governing healing. M.L.T.J. Muscles, Ligaments and Tendons Journal, 4 (2). pp. 245-255. ISSN 2240-4554
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Abstract
This review highlights recent research on Achilles tendon healing, and comments on the current clinical controversy surrounding the diagnosis and treatment of injury. The processes of Achilles tendon healing, as demonstrated through changes in its structure, composition, and biomechanics, are reviewed. Finally, a review of tendon developmental biology and mechano transductive pathways is completed to recognize recent efforts to augment injured Achilles tendons, and to suggest potential future strategies for therapeutic intervention and functional tissue engineering. Despite an abundance of clinical evidence suggesting that current treatments and rehabilitation strategies for Achilles tendon ruptures are equivocal, significant questions remain to fully elucidate the basic science mechanisms governing Achilles tendon injury, healing, treatment, and rehabilitation.
| Item Type: | Article |
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| Uncontrolled Keywords: | biomechanics, foot and ankle, tendinopathy, Achilles tendon rupture, injury, developmental biology, tissue engineering |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia > 617.1 Ferite e lesioni |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 20 May 2015 14:28 |
| Last Modified: | 20 May 2015 14:28 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/10926 |
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