Novel geometrical concept of a high-performance brain PET scanner. Principle, design and performance estimates

Séguinot, J. and Braem, A. and Chesi, E. and Joram, Christian and Mathot, S. and Weilhammer, P. and Chamizo Llatas, M. and Correia, J. G. and Ribeiro da Silva, M. and Garibaldi, F. and De Leo, R. and Nappi, E. and Corsi, F. and Dragone, A. and Schoenahl, F. and Zaidi, H. (2006) Novel geometrical concept of a high-performance brain PET scanner. Principle, design and performance estimates. Il nuovo cimento C, 29 (4). pp. 429-463. ISSN 1826-9885

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Abstract

We present the principle, a possible implementation and performance estimates of a novel geometrical concept for a high-resolution positron emission tomograph. The concept, which can be for example implemented in a brain PET device, promises to lead to an essentially parallax-free 3D image reconstruction with excellent spatial resolution and constrast, uniform over the complete field of view. The key components are matrices of long axially oriented scintillator crystals which are read out at both extremities by segmented Hybrid Photon Detectors. We discuss the relevant design considerations for a 3D axial PET camera module, motivate parameter and material choices, and estimate its performance in terms of spatial and energy resolution. We support these estimates by Monte Carlo simulations and in some cases by first experimental results. From the performance of a camera module, we extrapolate to the reconstruction resolution of a 3D axial PET scanner in a semi-analytical way and compare it to an existing state-of-the art brain PET device. We finally describe a dedicated data acquisition system, capable to fully exploit the advantages of the proposed concept. We conclude that the proposed 3D axial concept and the discussed implementation is a competitive approach for high-resolution brain PET. Excellent energy resolution and Compton enhanced sensitivity are expected to lead to high-quality reconstruction and reduced scanning times.

Item Type: Article
Uncontrolled Keywords: Medical imaging: general ; Positron emission tomography (PET) ; Instrumentation ; Scintillation detectors
Subjects: 500 Scienze naturali e Matematica > 530 Fisica
Depositing User: Marina Spanti
Date Deposited: 19 Mar 2020 14:28
Last Modified: 19 Mar 2020 14:28
URI: http://eprints.bice.rm.cnr.it/id/eprint/16102

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