Invasive Pneumococcal Disease Associated with Fanconi-Like Syndrome

Soh, Jade Xiao Jue and Goh, Raymond Kai Heng and Zheng, Shuwei (2019) Invasive Pneumococcal Disease Associated with Fanconi-Like Syndrome. European Journal of Case Reports in Internal Medicine, 6 (10). ISSN 2284-2594

[img]
Preview
Text
document.pdf - Published Version

Download (601kB) | Preview
Official URL: https://www.ejcrim.com/index.php/EJCRIM/article/vi...

Abstract

Acquired causes of Fanconi syndrome in adults are usually due to drugs, toxins or paraproteinaemias. Infectious causes are rarely described. We report a case of invasive pneumococcal disease in a patient who developed a Fanconi-like syndrome during the course of her illness. This patient presented with multiple electrolyte derangements consisting predominantly of hypokalaemia, hypomagnesaemia and hypophosphataemia during hospitalization for invasive pneumococcal disease with possible Austrian syndrome. Further evaluation revealed significant urinary losses of these electrolytes, uric acid and β2-microglobulin. Together with evidence of hypouricaemia, this is suggestive of proximal renal tubulopathy, and hence a Fanconi-like syndrome. The patient’s clinical condition and biochemical anomalies improved following pneumococcus treatment.

Item Type: Article
Uncontrolled Keywords: Pneumococcus, Streptococcus pneumoniae, Fanconi syndrome, proximal renal tubulopathy
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Chiara D'Arpa
Date Deposited: 19 Nov 2020 09:10
Last Modified: 19 Nov 2020 09:10
URI: http://eprints.bice.rm.cnr.it/id/eprint/19526

Actions (login required)

View Item View Item