Subcutaneous adipocytes may become osteoblasts

Ciuffi, Simone and Fabbri, Sergio and Zonefrati, Roberto and Galli, Gianna and Tanini, Annalisa and Brandi, Maria Luisa (2012) Subcutaneous adipocytes may become osteoblasts. Clinical cases in mineral and bone metabolism, 9 (1). pp. 28-30. ISSN 1971-3266

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Commonly, mesenchymal stem cells derived from bone marrow (BMSCs) are mainly utilized in regenerative medicine field. BMSCs are able to differentiate into several lineages, showing immunosuppressive properties, and they are genetically stable in long-term cultures. In the last years, another mesenchymal stem cells population, obtained from adipose tissue, defined adipose-derived stem/stromal cells (ASCs), it is under assessment of scientific research, as alternative to BMSCs. In fact, ASCs show similar capacity to BMSCs, but unlike BMSCs can be harvested more easily with an higher yield and with less invasive manipulation. In this review the abilities of ASCs to differentiate in osteoblasts cells are shown

Item Type: Article
Uncontrolled Keywords: Adipose-derived stem/stromal cells; adipose tissue; osteoblast; osteogenic differentiation
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 611 Anatomia; Citologia; Istologia umana > 611.7 Sistema muscoloscheletrico, tegumento
Depositing User: Danilo Dezzi
Date Deposited: 08 Jan 2014 09:47
Last Modified: 08 Jan 2014 09:47

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