FTIR microspectroscopic analysis: future perspectives

Paschalis, Eleftherios P. (2005) FTIR microspectroscopic analysis: future perspectives. Clinical cases in mineral and bone metabolism, 2 (2). pp. 143-149. ISSN 1971-3266

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It is widely accepted that bone strength depends on both its structural and material properties. The latter, although important, are difficult to establish until fairly recently. The new generation of infrared microspectroscopic and imaging instruments offers a unique tool in determining the material properties of bone as they allow the study of thin tissue sections and the determination of important parameters such as mineral maturity/crystallinity and collagen cross-links ratio in a spatially resolved manner, thus enabling the correlation with bone turnover. Despite the fact that the utility of such techniques as mass screening tools is currently debated since a biopsy is required, studies employing this technology have advanced our knowledge of the underlying mechanism of bone disease and the course of action of various therapeutic protocols.

Item Type: Article
Uncontrolled Keywords: Infrared spectroscopy, bone quality, osteoporosis, bone strength, mineral maturity, collagen cross-links
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User: Danilo Dezzi
Date Deposited: 24 Apr 2014 13:51
Last Modified: 24 Apr 2014 13:51
URI: http://eprints.bice.rm.cnr.it/id/eprint/8865

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