A future in our past: the umbilical cord for orthopaedic tissue engineering

Marmotti, Antonio and Peretti, Giuseppe Maria and Mattia, Silvia and Bonasia, Davide Edoardo and Bruzzone, Matteo and Dettoni, Federico and Rossi, Roberto and Castoldi, Filippo (2014) A future in our past: the umbilical cord for orthopaedic tissue engineering. Joints, 2 (1). pp. 20-25. ISSN 2282-4324

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Abstract

The umbilical cord (UC) has recently been added to the list of potential cell sources for tissue engineering and regenerative medicine purposes. Although the UC is usually discarded after delivery, UC storage in special tissue banks is becoming an increasingly common procedure. Indeed, the capacity of UC cells to be directed toward different phenotypes makes this tissue an ideal cell source for regenerative medicine in orthopedics and in other fields. In this paper, these issues are presented and discussed, together with the potential of this cell source for allogeneic use. This article also looks at the anatomy of the UC from both the macroscopic and the cellular perspective and considers its extraordinary potential for research and clinical applications.

Item Type:	Article
Uncontrolled Keywords:	Chondrogenic, osteogenic, mesenchymal stem cells, tissue engineering, umbilical cord
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia > 617.5 Medicina regionale; Chirurgia regionale
Depositing User:	Chiara D'Arpa
Date Deposited:	10 Nov 2014 11:33
Last Modified:	10 Nov 2014 11:33
URI:	http://eprints.bice.rm.cnr.it/id/eprint/10069

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