Morphogenesis of rat myotendinous junction

Curzi, Davide and Ambrogini, Patrizia and Falcieri, Elisabetta and Burattini, Sabrina (2013) Morphogenesis of rat myotendinous junction. M.L.T.J. Muscles, Ligaments and Tendons Journal, 3 (4). pp. 275-280. ISSN 2240-4554

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Abstract

Myotendinous junction (MTJ) is the highly specialized complex which connects the skeletal muscle to the tendon for transmitting the contractile force between the two tissues. The purpose of this study was to investigate the MTJ development and rat EDL was chosen as a model. 1, 15, 30 day animals were considered and the junctions were analyzed by light and electron microscopy. The MTJ interface architecture increased during the development, extending the interaction between muscle and tendon. 1-day-old rats showed disorganized myofibril bundles, spread cytosol and incomplete rough endoplasmic reticulum, features partially improved in 15-day-old rats, and completely developed in 30-day-old animals. These findings indicate that muscle-tendon interface displays, during rat lifetime, numerically increased and longer tendon interdigitations, correlated with an improved organization of both tissues and with a progressive acquirement of full functionality

Item Type:	Article
Uncontrolled Keywords:	Morphogenesis, myotendinous junction, skeletal muscle, ultrastructure
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User:	Danilo Dezzi
Date Deposited:	14 Nov 2014 16:53
Last Modified:	14 Nov 2014 16:53
URI:	http://eprints.bice.rm.cnr.it/id/eprint/10092

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