Finocchietto, Paola and Contardo, Damián and Uehara, Tatiana and Papini, Claudia and Deligiannis, Natalia and Darderes, Enrique and Castroagudin, Augusto and Cabral, Cecilia and Di Fonzo, Horacio (2015) TAFRO Syndrome in a Patient of South-American Descent. European Journal of Case Reports in Internal Medicine, 2 (4). pp. 1-3. ISSN 2284-2594
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Abstract
A 31-year-old Caucasian woman of South-American descent was diagnosed with a variant of multicentric Castleman disease (MCD) that has been reported in Japan as Castleman-Kojima disease. This is a systemic inflammatory disorder known as TAFRO Syndrome which includes thrombocytopenia, polyserositis (ascites/pleural effusion), microcytic anemia, myelofibrosis, fever, renal dysfunction and organomegaly, with immunologic disorder, polyclonal hypergammaglobulinemia, and elevated levels of interleukin-6 (IL-6) and the vascular endothelial growth factor present in serum and/or effusions. Optimal therapies are not well established. The patient was treated with methylprednisolone and rituximab. Following the start of treatment, the patient has been asymptomatic for over 8 months.
| Item Type: | Article |
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| Uncontrolled Keywords: | Castleman disease, TAFRO syndrome |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 14 Sep 2016 13:13 |
| Last Modified: | 14 Sep 2016 13:13 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/15039 |
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