Von Wowern, Fredrik Andreas and Brizzi, Marco and Holst, Jan Reversal of the Anticoagulation Effects of Dabigatran Etexilate by Idarucizumab in Three Patients Needing Urgent Surgical Intervention and One Case of Intravenous Thrombolysis in Ischaemic Stroke. European Journal of Case Reports in Internal Medicine, 4 (4). ISSN 2284-2594
|
Text
569-3554-1-PB.pdf - Published Version Download (177kB) | Preview |
Abstract
Objective: To describe the benefits of reversal of the anticoagulation effects of dabigatran etexilate in patients requiring urgent surgery or thrombolysis for ischaemic stroke. Materials and methods: Four patients, treated with dabigatran etexilate and presenting with cholecystitis, tibial fracture, lower limb ischaemia and ischaemic stroke, respectively. Results: Administration of idarucizumab normalized bleeding parameters and provided safe conditions for surgery and, in one case, successful thrombolysis of an ischaemic stroke. Conclusion: The introduction of an effective reversal agent for dabigatran etexilate allows physicians perform surgery under conditions of normal coagulation and permits thrombolysis in patients with ischaemic stroke despite being treated with dabigatran etexilate.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Pradaxa; Praxbind; NOAC; Surgery; Thrombolysis |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) |
| Depositing User: | Michela Donatelli |
| Date Deposited: | 27 Jun 2017 09:28 |
| Last Modified: | 27 Jun 2017 09:54 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/16424 |
Actions (login required)
 |
View Item |
