Ferreira, Sara and Vaz-Marques, Paula (2017) Tuberculous Tonsillitis in a Patient Treated with an Anti-TNF Ag. European Journal of Case Reports in Internal Medicine, 4 (8). ISSN 2284-2594
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Abstract
Tuberculosis remains a concern in patients receiving anti-TNF therapy as these individuals have a higher incidence of extrapulmonary and disseminated tuberculosis. Tuberculous tonsillitis is an unusual presentation of extrapulmonary tuberculosis, which is diagnosed mostly in immunodeficient patients. We report the case of a 33-year-old woman, diagnosed with Behçet’s syndrome, immunosuppressed with adalimumab, cyclosporine and prednisolone. She had odynophagia for 2 weeks, fever and a hypertrophied, ulcerated left tonsil. A tonsil biopsy revealed a granulomatous inflammatory process. Ziehl-Neelsen staining was positive for acid-fast bacilli. The chest x-ray revealed a milliary pattern. Gastric juice was positive for Mycobacterium tuberculosis complex DNA. A diagnosis of tonsillar and pulmonary tuberculosis was established. This case report highlights the low threshold for a tuberculosis diagnosis in unusual locations in patients treated with anti-TNF therapy.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Tuberculous tonsillitis, adalimumab |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Chiara D'Arpa |
| Date Deposited: | 26 Jan 2018 14:18 |
| Last Modified: | 26 Jan 2018 14:18 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/17003 |
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