Severe Acquired Coagulopathy During Fulminant Staphylococcus aureus Sepsis Most Likely Caused by S. aureus Exotoxins (SSLs)

Draaijers, Lonneke and Hassing, Robert-Jan and Kooistra, Menno and van Kessel, KoK and Hovens, Marcel (2018) Severe Acquired Coagulopathy During Fulminant Staphylococcus aureus Sepsis Most Likely Caused by S. aureus Exotoxins (SSLs). European Journal of Case Reports in Internal Medicine, 5 (12). ISSN 2284-2594

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Abstract

Haemostatic abnormalities frequently occur during sepsis and are most often attributed to disseminated intravascular coagulation (DIC). We report the case of a patient with severe coagulopathy acquired during fulminant S. aureus sepsis. DIC was not present. This coagulopathy was most likely caused by S. aureus exotoxins forming inhibitory complexes with coagulation factor Xa.

Item Type:	Article
Uncontrolled Keywords:	Staphylococcus aureus, coagulopathy, staphylococcal superantigen-like protein, coagulation factor Xa, disseminated intravascular coagulation
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User:	Greta Di Blasio
Date Deposited:	10 Jun 2019 16:10
Last Modified:	10 Jun 2019 16:10
URI:	http://eprints.bice.rm.cnr.it/id/eprint/18840

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