Metamizole-Induced Type I Kounis Syndrome

Lameiras, Catarina and Corte-Real, Ana and Órfão, Ana and Mendes Lopes, Marta and do Céu Dória, Maria (2021) Metamizole-Induced Type I Kounis Syndrome. European Journal of Case Reports in Internal Medicine, 8 (2). pp. 1-3. ISSN ISSN: 2284-2594

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Abstract

Kounis syndrome (KS) is defined as acute coronary syndrome (ACS) triggered by mast cell and platelet activation in the setting of allergic or anaphylactic insults. KS is a unique and complex cause of ACS and many cases may be missed due to its highly variable clinical manifestations. In this report, we present a case of KS type I triggered by metamizole in the absence of a previous history of allergy to this drug. Following the administration of metamizole, the patient developed generalized acute urticaria, chest pain and diaphoresis. Electrocardiography (ECG) showed ST-segment elevation suggestive of myocardial infarction complicated by ventricular tachycardia. No coronary disease was observed on coronary angiography. The cardiac manifestations of KS may be life-threatening, and so it is important to appropriately recognize and treat this condition.

Item Type: Article
Uncontrolled Keywords: Kounis syndrome, anaphylactic reaction, myocardial infarction, metamizole
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 20 Dec 2021 15:24
Last Modified: 20 Dec 2021 15:24
URI: http://eprints.bice.rm.cnr.it/id/eprint/21186

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