Severe Complication of Thiopurine Treatment in a Young Woman with Crohn’s Disease

Voet, MPJ and Calon, TGA and Hendriks, MMC and Schreuder, RM (2021) Severe Complication of Thiopurine Treatment in a Young Woman with Crohn’s Disease. European Journal of Case Reports in Internal Medicine, 8 (3). pp. 1-3. ISSN ISSN: 2284-2594

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Abstract

Case description: A 28-year old woman receiving thiopurine treatment for Crohn’s disease presented with a systemic primo cytomegalovirus (CMV) infection affecting the gut (colitis), liver (hepatitis), lungs (pneumonitis) and eyes (retinitis). Secondary to this systemic infection, she developed splenomegaly, pancytopenia and lymphadenopathy. Anti-viral treatment resulted in complete resolution of clinical, biochemical and radiological abnormalities within 6 weeks. Conclusion: Early recognition is crucial since CMV infection in a patient receiving thiopurine treatment may result in serious complications.

Item Type: Article
Uncontrolled Keywords: Cytomegalovirus, thiopurine, pneumonitis, colitis, hepatitis
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 21 Dec 2021 14:43
Last Modified: 21 Dec 2021 14:43
URI: http://eprints.bice.rm.cnr.it/id/eprint/21195

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