Myasthenia Gravis Revealing Hodgkin’s Lymphoma

Yousfi, Jaouad and Bensalek, Fatimazahra and Zahlane, Mouna and Benjilali, Laila and Essaadouni, Lamiaa (2021) Myasthenia Gravis Revealing Hodgkin’s Lymphoma. European Journal of Case Reports in Internal Medicine, 8 (3). pp. 1-4. ISSN ISSN: 2284-2594

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Abstract

Introduction: Myasthenia gravis is a rare autoimmune disease caused by autoantibodies directed against the synapses of the neuromuscular junction. Patient and methods: We report the case of a young patient with myasthenia gravis associated with Hodgkin's lymphoma. Results: A 22-year-old patient presented with a 2-month history of severe weakness associated with muscle fatigability and intermittent ptosis without dysphonia or respiratory signs. Clinical examination revealed generalized myasthenia. The EMG did not show post-synaptic block, and anti-acetylcholine receptor antibodies were elevated at 3 nmol/l (normal ≤0.3 nmol/l). CT of the thorax showed an anterior medial mass. Immunohistochemistry of the mass revealed mixed cellularity Hodgkin’s lymphoma. Conclusion: The association of lymphomas with myasthenia gravis has been rarely reported.

Item Type: Article
Uncontrolled Keywords: Myasthenia gravis, paraneoplastic, Hodgkin's lymphoma
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 21 Dec 2021 14:52
Last Modified: 21 Dec 2021 14:52
URI: http://eprints.bice.rm.cnr.it/id/eprint/21208

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