Investigating Febrile Polyserositis: An Unusual Case of Idiopathic Hypereosinophilic Syndrome

Rueff Rato, Inês and Rigor, Joana and Ferreira, Paula and Laranjinha, Joana and Santos-Silva, Gualter and Martins-Mendes, Daniela (2021) Investigating Febrile Polyserositis: An Unusual Case of Idiopathic Hypereosinophilic Syndrome. European Journal of Case Reports in Internal Medicine, 8 (4). pp. 1-5. ISSN ISSN: 2284-2594

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Abstract

Hypereosinophilic syndrome (HES) is a heterogenous group of diseases characterized by abnormal accumulation of eosinophils in the blood or peripheral tissues. It can affect all organs and therefore clinical manifestations are highly variable. We describe the case of a 38-yearold man admitted for febrile polyserositis. He developed cardiac tamponade requiring pericardiocentesis complicated by left ventricle perforation which was successfully repaired. He presented mild peripheral eosinophilia. Bronchoalveolar lavage evidenced eosinophilic alveolitis, and pleural and pericardium histopathology revealed the presence of abundant eosinophils. All other causes of tissue eosinophilia were excluded and the diagnosis of idiopathic HES was made. The patient was started on glucocorticoids with resolution of symptoms. This case report describes a rare but potentially fatal presentation of HES and demonstrates the difficulty and delay in diagnosis when peripheral hypereosinophilia is absent.

Item Type: Article
Uncontrolled Keywords: Hypereosinophilic syndrome, polyserositis, eosinophilic alveolitis, eosinophilic pleurisy, eosinophilic pericarditis
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 21 Dec 2021 15:08
Last Modified: 21 Dec 2021 15:08
URI: http://eprints.bice.rm.cnr.it/id/eprint/21234

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