Photosensitizing proteins for a targeted antibacterial photodynamic inactivation

Mussini, A. and Hally, C. and Viappiani, C. and Nonell, S. and Agut Bonsfills, M. and Abbruzzetti, S. (2021) Photosensitizing proteins for a targeted antibacterial photodynamic inactivation. Il nuovo cimento C, 44 (4-5). pp. 1-4. ISSN 1826-9885

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Abstract

One of the emerging global health threats is the drug-resistant microbial diseases that could cause millions of deaths each year by 2050. A very promising tool to tackle antimicrobial resistance is photodynamic therapy that exploits the ability of a photosensitizer to generate oxidizing species upon illumination to kill bacteria. The research activity in this field is very active and, following this approach, we aim to develop a targeted theranostic agent where a protein is used as a “modular” carrier, transporting a fluorescent photosensitizer, and an antibody to confer selectivity to the photodynamic effect.

Item Type: Article
Subjects: 500 Scienze naturali e Matematica > 530 Fisica
Depositing User: Marina Spanti
Date Deposited: 20 Sep 2021 09:41
Last Modified: 20 Sep 2021 09:41
URI: http://eprints.bice.rm.cnr.it/id/eprint/21336

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