Ejikeme, Chidinma and Elkattawy, Sherif and Kayode-Ajala, Fisayo and Ayad, Sarah and Al-nasseri, Abraheim and Kessler, William (2021) Reactive Thrombocytosis after Splenectomy in Hereditary Spherocytosis: Case Report and Literature Review. European Journal of Case Reports in Internal Medicine, 8 (7). pp. 1-3. ISSN 2284-2594
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Abstract
Reactive thrombocytosis after splenectomy is a feared cause of thrombosis throughout the arterial and venous system. There are many causes of splenomegaly, ranging from cirrhosis to lymphoma to hereditary spherocytosis. In this report, we will discuss a case of reactive thrombocytosis after splenectomy in a patient with hereditary spherocytosis. Splenomegaly is a relatively common finding in HD patients, causing extravascular haemolysis and thus leading to haemolytic anaemia. Splenectomy is usually considered when patients start to manifest severe symptoms such as abdominal pain, jaundice or worsening liver function tests. Our patient was a good surgical candidate and successfully underwent splenectomy but afterwards developed arterial and venous thrombosis due to reactive thrombocytosis. An extensive hypercoagulable work-up was unremarkable. The patient was started on hydroxyurea and anticoagulation with eventual improvement of platelet levels.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Thrombocytosis, splenomegaly, hereditary spherocytosis, thrombosis, hypercoagulable |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 25 Jan 2022 15:57 |
| Last Modified: | 25 Jan 2022 15:57 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21439 |
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