Gadaen, Rens JR and Tummers-de Lind van Wijngaarden, Roderick F (2021) Hypothyroid Crisis: Oral or Intravenous Treatment? A Report of Two Cases. European Journal of Case Reports in Internal Medicine, 8 (9). pp. 1-4. ISSN 2284-2594
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Abstract
Background: Hypothyroid crisis, or myxoedema coma, is a rare condition with high mortality and must be treated promptly. Even though it may be unfavourable, most guidelines only focus on intravenous drug administration due to lack of data on oral treatment.Methods/Results: The course of oral treatment in two patients admitted in our hospital is described. Patients were treated with levothyroxine 1.3 μg/kg and liothyronine 25 μg twice daily, followed after 1 week with only levothyroxine 1.3 μg/kg daily. Oral treatment was successful in both patients without complications or side-effects. Conclusions: Oral substitution is an appropriate alternative to intravenous substitution, which has potential disadvantages and is associated with higher mortality.
| Item Type: | Article |
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| Uncontrolled Keywords: | Hypothyroid crisis, myxoedema coma, oral treatment |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 25 Jan 2022 16:36 |
| Last Modified: | 25 Jan 2022 16:36 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21459 |
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