Fulminant Haemolysis Following Endoscopic Retrograde Cholangiopancreatography

Bibi, Mário and Viana, Susana and Leitão, Cátia and Moço, Rui and Eremina, Yuliana O. (2021) Fulminant Haemolysis Following Endoscopic Retrograde Cholangiopancreatography. European Journal of Case Reports in Internal Medicine, 8 (9). pp. 1-3. ISSN 2284-2594

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Abstract

We report the case of a 77-year-old-man with a history of type 2 diabetes mellitus who underwent endoscopic retrograde cholangiopancreatography (ERCP) because of a gallstone in the common bile duct. Thirty-six hours after the procedure, the patient developed persistent fever and epigastric pain associated with de novo jaundice. Massive haemolysis (with exuberant spherocytosis) occurred and patient died in 3 hours. Clostridium perfringens was isolated in the blood cultures. Massive haemolysis associated with C. perfringens has a high mortality rate. Management involves a high index of suspicion after gastrointestinal procedures like ERCP, surgical consultation, antibiotic therapy, transfusion of red cell concentrates and, potentially, hyperbaric oxygen therapy.

Item Type: Article
Uncontrolled Keywords: Clostridium perfringens, haemolysis, spherocytosis, endoscopic retrograde cholangiopancreatography, sepsis
Subjects: 600 Tecnologia - Scienze applicate
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale)
Depositing User: Marina Spanti
Date Deposited: 15 Dec 2021 12:41
Last Modified: 15 Dec 2021 12:41
URI: http://eprints.bice.rm.cnr.it/id/eprint/21466

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