Bibi, Mário and Viana, Susana and Leitão, Cátia and Moço, Rui and Eremina, Yuliana O. (2021) Fulminant Haemolysis Following Endoscopic Retrograde Cholangiopancreatography. European Journal of Case Reports in Internal Medicine, 8 (9). pp. 1-3. ISSN 2284-2594
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Abstract
We report the case of a 77-year-old-man with a history of type 2 diabetes mellitus who underwent endoscopic retrograde cholangiopancreatography (ERCP) because of a gallstone in the common bile duct. Thirty-six hours after the procedure, the patient developed persistent fever and epigastric pain associated with de novo jaundice. Massive haemolysis (with exuberant spherocytosis) occurred and patient died in 3 hours. Clostridium perfringens was isolated in the blood cultures. Massive haemolysis associated with C. perfringens has a high mortality rate. Management involves a high index of suspicion after gastrointestinal procedures like ERCP, surgical consultation, antibiotic therapy, transfusion of red cell concentrates and, potentially, hyperbaric oxygen therapy.
Item Type: | Article |
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Uncontrolled Keywords: | Clostridium perfringens, haemolysis, spherocytosis, endoscopic retrograde cholangiopancreatography, sepsis |
Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
Depositing User: | Marina Spanti |
Date Deposited: | 15 Dec 2021 12:41 |
Last Modified: | 15 Dec 2021 12:41 |
URI: | http://eprints.bice.rm.cnr.it/id/eprint/21466 |
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