Miante, Silvia and Puthenparampil, Marco and Margoni, Monica and Rinaldi, Francesca and Gallo, Paolo and Perini, Paola (2021) Multiple Sclerosis-Related “Spasticity-Plus Syndrome” May Benefit from Early Nabiximols Treatment. European Journal of Case Reports in Internal Medicine, 8 (Sup 2). pp. 34-36. ISSN 2284-2594
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Abstract
We present the case of a 42-year-old woman affected by relapsing-remitting multiple sclerosis who presented an extensive involvement of the spinal cord during the disease course. After a trial on first-line treatment, which she discontinued due to poor compliance, she was switched to intravenous ocrelizumab 600 mg every 6 months. At 10 years from the disease onset, as a result of the extensive spinal cord involvement, she began to complain of progressive and rapid reduction in ambulatory performance due to spasticity of the right leg, instability and severe fatigability, together with overactive bladder symptoms. The early introduction of nabiximols positively impacted on the patient’s symptoms and on the neurological examination, as well as on her quality of life.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Spasticity, nabiximols, multiple sclerosis, fatigues |
| Subjects: | 600 Tecnologia - Scienze applicate 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 19 Jan 2022 17:08 |
| Last Modified: | 19 Jan 2022 17:08 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21481 |
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