Mekheal, Erinie and Roman, Sherif and Kania, Brooke and Mekheal, Nader and Awasthi, Sharon and Kumar, Vinod and Maroules, Michael (2022) A Rare Case of Benign Histiocytic Neoplasm of Cutaneous Rosai–Dorfman Disease: A Case Report and Literature Review. European Journal of Case Reports in Internal Medicine, 9 (2). pp. 1-4. ISSN 2284-2594
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Abstract
Rosai–Dorfman disease (RDD) is a rare disorder characterized by the proliferation of histiocytes in lymph nodes. It can occur anywhere in the body but commonly involves the cervical area of the neck. Its clinical presentation varies and patients with skin manifestations may develop papules, nodules, plaques, or pustules. Histologically, it typically presents with emperipolesis, where intact lymphocytes are found within histiocytes. The definitive treatment of RDD is not well established given the rarity of the disease and indeed skin lesions can regress spontaneously. Therapeutic treatment options include cryotherapy, radiation, or topical agents such as steroids or retinoids. Here we describe the case of a 24-year-old Hispanic female who presented with skin manifestations which proved to be histologically positive for Rosai–Dorfman disease. The patient clinically improved following the administration of intralesional steroids.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Rosai–Dorfman disease, cutaneous type, lymphoproliferative disorder, emperipolesis |
| Subjects: | 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) |
| Depositing User: | Marina Spanti |
| Date Deposited: | 14 Apr 2022 12:37 |
| Last Modified: | 14 Apr 2022 12:37 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/21801 |
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