Use of Midodrine in Heart Failure: Two Case Reports and a Review of the Literature

Hajjiah, Adnan and Maadarani, Ossama and Bitar, Zouheir and Hanna, Boutros and Elshabasy, Ragab and Abdelfatah, Mohammad and Gohar, Mohammad (2022) Use of Midodrine in Heart Failure: Two Case Reports and a Review of the Literature. European Journal of Case Reports in Internal Medicine, 9 (3). pp. 1-4. ISSN 2284-2594

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Abstract

Hypotension in patients with heart failure is much more frequent in daily clinical practice than the 10–15% reported in clinical trials. In patients with heart failure with reduced ejection fraction (HFrEF), hypotension frequently limits the initiation and up-titration of guideline-directed medical therapy (GDMT). Midodrine is a peripheral alpha-1 agonist and a vasopressor anti-hypotensive agent approved for the treatment of orthostatic hypotension. We describe two cases where midodrine was prescribed in patients with HFrEF and hypotension.

Item Type: Article
Uncontrolled Keywords: Midodrine, heart failure, noradrenaline
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici)
Depositing User: Marina Spanti
Date Deposited: 14 Apr 2022 13:11
Last Modified: 14 Apr 2022 13:11
URI: http://eprints.bice.rm.cnr.it/id/eprint/21818

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