Cozza, F. and Lizio, A. and Greco, L. and Bona, S. (2023) Optometric assessment in amyotrophic lateral sclerosis patients: A focus on the relation between ocular motility disturbances and cognitive findings. Il nuovo cimento C, 46 (5). pp. 1-4. ISSN 1826-9885
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Abstract
Background and Purpose To assess the visual function in a large cohort of Amyotrophic Lateral Sclerosis (ALS) patients in different stages of the disease through optometric assessment, and to evaluate the relation between ocular motility and cognitive data in a subgroup of patients. Methods The optometric pro- tocol included ocular motility tests (broad H test and Northeastern State University College of Optometry - NSUCO test), near point of convergence (NPC), refractive error, best corrected visual acuity, binocular visual alignment assessment, and ocular symptoms questionnaire. The functional measure was expressed by ALS Functional Rating Scale-revised (ALSFRS-r) and the cognitive impairment was assessed by the Edinburgh Cognitive and Behavioural ALS Screen (ECAS). Demographic and clini- cal features were also collected. Results Two-hundred consecutive ALS patients (me- dian age: 64; M/F: 118/82) in different stages of disease were recruited. Regarding ocular motility tests, patients with acceptable NSUCO values in both saccades and pursuits performance, obtained a significantly higher ECAS total score and most of the domains. Conclusions This study highlights the importance of optometric evaluations in multidisciplinary assessment to take care of ocular impairment early in the disease process. Our results seem to confirm the association between ocular motility disturbances and cognitive dysfunction, consistently with the literature.
| Item Type: | Article |
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| Subjects: | 500 Scienze naturali e Matematica > 530 Fisica |
| Depositing User: | Marina Spanti |
| Date Deposited: | 15 Mar 2024 15:40 |
| Last Modified: | 15 Mar 2024 15:40 |
| URI: | http://eprints.bice.rm.cnr.it/id/eprint/22748 |
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