Psychometric properties of the Italian version of the Guy's Neurological Disability Scale

Pappalardo, Angelo and Patti, Francesco (2010) Psychometric properties of the Italian version of the Guy's Neurological Disability Scale. Functional Neurology; New Trends in Interventional Neurosciences, 25 (4). pp. 223-233. ISSN 1971-3274

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Abstract

The aim of this study was to assess the reliability, validity and sensitivity of the Guy’s Neurological Disability Scale (GNDS) translated into Italian and administered to Italian-speaking patients with multiple sclerosis (MS). In total, 202 outpatients with MS were enrolled in the study; 153 had relapsing-remitting (RR) MS and 49 had secondary progressive (SP) MS; 189 healthy individuals were recruited as control subjects. Inter-rater agreement, as expressed by the alpha coefficient, was 0.83. Intra-rater agreement was 0.91. Compared with the healthy subjects, the MS patients recorded significantly higher mean total scores on the Italian version of the GNDS. The mean GNDS total score of the patients with RRMS was significantly lower than that of the patients with SPMS. Cross-sectional correlations between the GNDS and the Expanded Disability Status Scale were significant in the whole sample (r=0.77; p<0.001), in the RRMS patients (r=0.65, p<0.01), and in those with SPMS (r=0.48, p<0.05). In conclusion, the Italian version of the GNDS emerges as a valid assessment instrument with adequate basic psychometric properties

Item Type:	Article
Uncontrolled Keywords:	Assessment, disability, multiple sclerosis
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia) > 616.83 Altre malattie organiche del sistema nervoso centrale (Include la corea ed i disturbi coreici ad eccezione della malattia di Huntington (in 616.851) (Classificare qui, in 616.83, le malattie dei gangli vasali, del midollo spinale) > 616.834 Sclerosi multipla
Depositing User:	Danilo Dezzi
Date Deposited:	02 Jul 2012 07:27
Last Modified:	02 Jul 2012 07:27
URI:	http://eprints.bice.rm.cnr.it/id/eprint/3587

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