Using neuroimaging to detect awareness in disorders of consciousness

Owen, Adrian M. and Coleman, Martin R. (2008) Using neuroimaging to detect awareness in disorders of consciousness. Functional Neurology; New Trends in Interventional Neurosciences, 23 (4). pp. 189-194. ISSN 1971-3274

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Abstract

The assessment of residual brain function in the vegetative state is extremely difficult and depends frequently on subjective interpretations of observed spontaneous and volitional behaviours. For those patients who retain peripheral motor function, rigorous behavioural assessment supported by structural imaging and electrophysiology is usually sufficient to establish a patient’s level of wakefulness and awareness. However, it is becoming increasingly apparent that, in some patients, damage to the peripheral motor system may prevent overt responses to commands, even though the cognitive ability to perceive and understand such commands may remain intact. Advances in functional neuroimaging suggest a novel solution to this problem; in several recent cases, so-called activation studies have been used to identify residual cognitive function and even conscious awareness in patients who are assumed to be vegetative, yet retain cognitive abilities that have evaded detection using standard clinical methods

Item Type:	Article
Uncontrolled Keywords:	Disorders of consciousness, IMRI, functional neuroimaging, minimally conscious state, vegetative state
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia) > 616.8047548 Sistema Nervoso – Risonanza magnetica nucleare (Classificare qui: Neuroimaging, Neuroimaging funzionale, Cervello - Risonanza magnetica funzionale, Cervello - Risonanza magnetica per immagini) 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.8 Malattie del sistema nervoso e disturbi mentali (Classificare qui la Neuropsichiatria, la Neurologia) > 616.84 Manifestazioni delle malattie neurologiche (Classificare qui la patologia, la diagnosi, il trattamento dei sintomi) > 616.849 Sintomi vari (Include il coma, il dolore, l’enuresi, disturbi della coscienza)
Depositing User:	Danilo Dezzi
Date Deposited:	09 Jul 2012 14:05
Last Modified:	09 Jul 2012 14:05
URI:	http://eprints.bice.rm.cnr.it/id/eprint/3701

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