Systemic mastocytosis with skeletal involvement: a case report and review of the literature

Benucci, Maurizio and Bettazzi, Catia and Bracci, Stefania and Fabiani, Plinio and Monsacchi, Laura and Cappelletti, Carlo and Manfredi, Mariangela and Ciolli, Stefania (2009) Systemic mastocytosis with skeletal involvement: a case report and review of the literature. Clinical cases in mineral and bone metabolism, 6 (1). pp. 66-70. ISSN 1971-3266

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Abstract

Systemic Mastocytosis (SM) comprises a heterogeneous group of disorders of mast cell proliferation. Infiltration, including skin and bone, of multiple mast cells may occur as cutaneous and systemic variants. A rare form of osteoporosis has been also described as expression of the skeletal involvement. Here, we describe a case of a 57-years-old woman with SM and, according to the clinical diagnosis, evaluate the possible mechanism underlying osteoporosis. Moreover, a review of the literature, particularly regarding the use of bisphosphonates in this rare disease is also presented.

Item Type:	Article
Uncontrolled Keywords:	Mastocytosis, osteoporosis, bisphosphonates
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 611 Anatomia; Citologia; Istologia umana > 611.7 Sistema muscoloscheletrico, tegumento
Depositing User:	Danilo Dezzi
Date Deposited:	16 Jan 2014 14:13
Last Modified:	16 Jan 2014 14:13
URI:	http://eprints.bice.rm.cnr.it/id/eprint/5412

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