Preterm delivery at low gestational age: risk factors for short latency. A multivariated analysis

Marzano, Sara and Padula, Francesco and Meloni, Paolo and Anceschi, Maurizio Marco (2008) Preterm delivery at low gestational age: risk factors for short latency. A multivariated analysis. Journal of prenatal medicine, 2 (2). pp. 15-18. ISSN 1971-3290

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Abstract

Objective. The aim of this study is to identify the risk factors for a short latency in preterm delivery at low gestational ages (GA). Study design. A retrospective analysis involving, between January 2004 and May 2006, 204 singleton pregnancies with admission diagnosis of preterm labor and, in particular, 91 pregnant women admitted between 24+0 and 31+6 weeks’ gestation. Results. In pregnant women with a diagnosis of preterm labor at 24-31+6 weeks’ gestation, at ROC curve, a value of considering WBC and cervical dilatation, combined in the following formula (75.237 - (2.290 * “WBC”) - (10.787 * “cervical dilatation”)) <=33.101 has a 74.2% Sensitivity and a 78.3% Specificity in predicting a latency =< 4 days (+LR 3.42 and -LR 0.33) and a 70% Sensitivity and a 84.3% Specificity in predicting GA at delivery at 24-31 weeks’ gestation (+LR 4.46 and -LR 0.36). Conclusion. We suggest a more strictly monitoring and a more aggressive therapy in presence of prognostic parameters of shorter latency.

Item Type:	Article
Uncontrolled Keywords:	Preterm labor, preterm delivery, latency
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 618 Altri rami della medicina; Ginecologia e ostetricia, Pediatria, Geriatria > 618.4 Parto, travaglio
Depositing User:	Gianni Aiello
Date Deposited:	10 Feb 2014 16:39
Last Modified:	10 Feb 2014 16:39
URI:	http://eprints.bice.rm.cnr.it/id/eprint/5678

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