Hypervitaminosis D: case report of pediatric osteoporosis secondary to cystic fibrosis

Cialdella, Pietro and Carella, Francesco (2011) Hypervitaminosis D: case report of pediatric osteoporosis secondary to cystic fibrosis. Clinical cases in mineral and bone metabolism, 8 (3). pp. 66-68. ISSN 1971-3266

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Abstract

The objective of the study is to evaluate alterations of bone metabolism in adolescence and adult CF, determining the rate of osteoporosis, osteopenia and vertebral and non-vertebral fractures. We took into account the clinical case of a child who right from the age of seven years has presented joint pain. The little girl was diagnosed with osteopenia taken with therapy of calcium and vitamin D; after few years despite treatment nephrocalcinosis and osteoporosis take over. It was examined a cohort of patients with cystic fibrosis of the southern Italy, 24 patients aged between 12 and 44 years, 12 females and 12 males with BMD assessment methods like dual energy X-rays (DXA) and calcaneal ultrasound densitometry in a few cases, ultrasonography was used jointly. From this case study we tried to establish the relationship between cystic fibrosis and osteoporosis etiopathogenetic, the adoptive therapy and the impact of therapies on patients. It was concluded that, given the high number of unrecognized patients with impaired bone mineralization, we must implement and integrate a more aggressive treatment with bisphosphonates and prevention programs that can combat the lifestyle and new eating habits of our young people that facilitate the loss of bone mass

Item Type:	Article
Uncontrolled Keywords:	Cystic fibrosis; osteoporosis; hypercalciuria
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 611 Anatomia; Citologia; Istologia umana > 611.7 Sistema muscoloscheletrico, tegumento
Depositing User:	Danilo Dezzi
Date Deposited:	08 Jan 2014 11:42
Last Modified:	08 Jan 2014 11:42
URI:	http://eprints.bice.rm.cnr.it/id/eprint/6019

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