Osteoporosis and aromatase inhibitors: experience and future prospects

Bosco, Daniela (2012) Osteoporosis and aromatase inhibitors: experience and future prospects. Clinical cases in mineral and bone metabolism, 9 (2). pp. 89-91. ISSN 1971-3266

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Abstract

Introduction. The aim of this study is to improve the assistance given to patients under treatment with aromatase inhibitors in order to prevent secondary osteoporosis through the planning of an awareness programme for the oncologist and offering a facilitated treatment path. Materials and methods. Thirty-nine postmenopausal women treated with aromatase inhibitors for breast cancer were selected. For each subject, the age at the beginning of the therapy, the type of aromatase inhibitors and the age at the performance of the bone densitometry was registered. In addition, the use of osteoporosis medication and supplementation of calcium and vitamin D were evaluated. Participants were required to answer a questionnaire consisting of closed questions relating to booking procedures of the bone densitometry and about their own knowledge of osteoporosis related to the use of aromatase inhibitors. Conclusions. Although there is evidence of negative impact of the aromatase inhibitors on bone, our data still show a poor application of the recommendations in order to prevent osteoporosis related to the administration of these drugs. Our suggestion is a more active implementation of the guidelines, also by means of a greater collaboration between the oncologist and the specialist in osteoporosis, and the offer of a diagnostic and therapeutic pathway

Item Type:	Article
Uncontrolled Keywords:	Aromatase inhibitors; breast cancer; osteoporosis
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 611 Anatomia; Citologia; Istologia umana > 611.7 Sistema muscoloscheletrico, tegumento
Depositing User:	Danilo Dezzi
Date Deposited:	03 Dec 2013 14:56
Last Modified:	03 Dec 2013 14:56
URI:	http://eprints.bice.rm.cnr.it/id/eprint/6040

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