Multicentric osteolytic lesion of the middle finger of the hand. Case report

Monacelli, Giampaolo P. and Rizzo, Maria Ida and Monarca, Cristiano (2012) Multicentric osteolytic lesion of the middle finger of the hand. Case report. Il giornale di chirurgia, 33 (4). pp. 136-138. ISSN 1971-145X

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Abstract

Giant cell-rich osteolytic lesions may have overlapping clinical, radiologic, and histopathologic features, with an important degree of difficulty of diagnosis and treatment. We report a case of double osteolytic lesion at the middle-finger in a young man without previous history of hand trauma. He underwent en-bloc resection of the bone lesions and reconstruction by graft of hydroxyapatite, resulting in a good morpho-functional result. Histological diagnosis was giant cell reparative granuloma (GCRG), although several features were considered atypical, including the appearance of the giant cells and the areas of the stroma that more closely resembled a giant cell tumor. GCRG is a benign rare intraosseous lesion and the true nature is controversial and unknown. The theories are that it could be a reactive lesion, a developmental anomaly or a benign neoplasm. It appears as an osteolytic lesion that must be considered in the differential diagnosis of other “critical” bone lesions similar in clinical, as well as radiologic and pathological appearance. Further characterization studies are helpful and necessary for the proper management.

Item Type:	Article
Uncontrolled Keywords:	Hand - Osteolytic lesions - Giant cell reparative granuloma - Surgery
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia > 617.4 Chirurgia secondo il Sistema e Regioni
Depositing User:	Nadia Del Gobbo
Date Deposited:	16 Jun 2016 10:21
Last Modified:	16 Jun 2016 10:21
URI:	http://eprints.bice.rm.cnr.it/id/eprint/7902

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