Eosinophilic cystitis associated with urethral stricture disease from pelvic trauma. Case report and literature review

Martino, Giovanni and Torcasio, Angelo and Iavarone, Claudio and Cardarelli, A. and Monti, Massimo (2005) Eosinophilic cystitis associated with urethral stricture disease from pelvic trauma. Case report and literature review. Il giornale di chirurgia, 26 (11/12). pp. 425-429. ISSN 1971-145x

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Abstract

We report a case of eosinophilic cystitis (EC) in a 65-year-old man with urethral stricture disease from blunt pelvic traumatic event. EC is a rare condition characterized by eosinophilic infiltration of the bladder wall, that usually presents with irritative voiding symptoms, suprapubic pain and hematuria. Etiology is still not clear although a review of the literature suggests that pathogenetic mechanisms probably engage an altered immune response in the bladder, with the inflammatory reaction caused by factors such as exogenous allergens and previous bladder injury or surgery to the bladder or the prostate. The diagnosis of EC has to be confirmed by biopsy, since in some cases it may manifest as other inflammatory and malignant bladder disorders. A conservative medical management is indicated initially, since this disease may be self-limited, with a benign course especially in children and young patients. In adults EC is more often a chronic recurrent condition that requires close follow-up since it may lead to serious progressive bladder and/or upper urinary tract disease. More invasive therapies (including transurethral resection, partial or total cystectomy) may also be required when conservative therapy fails.

Item Type:	Article
Uncontrolled Keywords:	Eosinophilic cystitis, Male-urethral stricture; Cistite eosinofila, Stenosi uretra maschile
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 617 Rami vari della medicina; Chirurgia
Depositing User:	Chiara D'Arpa
Date Deposited:	03 Sep 2014 08:55
Last Modified:	03 Sep 2014 08:55
URI:	http://eprints.bice.rm.cnr.it/id/eprint/7980

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