Stem cells and tendinopathy: state of the art from the basic science to clinic application

Ruzzini, Laura and Longo, Umile Giuseppe and Rizzello, Giacomo and Denaro, Vincenzo (2012) Stem cells and tendinopathy: state of the art from the basic science to clinic application. M.L.T.J. Muscles, Ligaments and Tendons Journal, 2 (3). pp. 235-238. ISSN 2240-4554

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Abstract

Management of tendinopathies and tendon rupture is challenging. In the last few decades, several emerging strategies including tissue engineering with mesenchymal stem cells have been proposed to enhance tendon healing. They hold the promise to yield more successful outcomes for the management of patients with tendon pathology. Current in vitro studies support the application of these cell-based therapies for the regeneration of tendon tissues. However, these cell-based strategies have been investigated only in pre-clinical studies and the role of stem cells needs to be confirmed. We performed a review of the literature to focus on actual knowledge and the future perspectives of stem cells for tendon regeneration and tendon engineering

Item Type:	Article
Uncontrolled Keywords:	Tendon, mesenchymal stem cells, tendon stem cells, tendinopathy
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User:	Danilo Dezzi
Date Deposited:	16 Apr 2014 16:38
Last Modified:	16 Apr 2014 16:38
URI:	http://eprints.bice.rm.cnr.it/id/eprint/8148

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