Augmenting tendon and ligament repair with platelet-rich plasma (PRP)

Yuan, Ting and Zhang, Chang-Qing and Wang, James H-C. (2013) Augmenting tendon and ligament repair with platelet-rich plasma (PRP). M.L.T.J. Muscles, Ligaments and Tendons Journal, 3 (3). pp. 139-149. ISSN 2240-4554

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Abstract

Tendon and ligament injuries (TLI) commonly occur in athletes and non-athletes alike, and remarkably debilitate patients’ athletic and personal abilities. Current clinical treatments, such as reconstruction surgeries, do not adequately heal these injuries and often result in the formation of scar tissue that is prone to re-injury. Platelet-rich plasma (PRP) is a widely used alternative option that is also safe because of its autologous nature. PRP contains a number of growth factors that are responsible for its potential to heal TLIs effectively. In this review, we provide a comprehensive report on PRP. While basic science studies in general indicate the potential of PRP to treat TLIs effectively, a review of existing literature on the clinical use of PRP for the treatment of TLIs indicates a lack of consensus due to varied treatment outcomes. This suggests that current PRP treatment protocols for TLIs may not be optimal, and that not all TLIs may be effectively treated with PRP. Certainly, addi t ional basic science studies are needed to develop optimal treatment protocols and determine those TLI conditions that can be treated effectively

Item Type:	Article
Uncontrolled Keywords:	Tendon and ligament injury, tendinopathy
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User:	Danilo Dezzi
Date Deposited:	17 Apr 2014 14:24
Last Modified:	17 Apr 2014 14:24
URI:	http://eprints.bice.rm.cnr.it/id/eprint/8268

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