Selenium in the thyroid: physiology and pathology

De Fusco, Carolina and Nettore, Immacolata Cristina and Colao, Annamaria and Macchia, P.E. (2013) Selenium in the thyroid: physiology and pathology. Reviews in endocrinology and metabolism, 1 (1). pp. 34-40. ISSN 2282-8362

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Abstract

Selenium (Se) is a trace element that plays a critical role in several processes for human health. The thyroid is the organ with the highest Se content per gram of tissue; in thyroid follicular cells, Se acts as antioxidant by contrasting the production of the reactive oxygen species that are generated during thyroid hormones biosynthesis. In addition, Se is part of the active site of the deoidinases, the enzymes responsible for thyroid hormones activation and inactivation. Herein, the effects of Se supplementation in patients with thyroid related disorders have been reviewed on the basis of the studies published on this issue.

Item Type:	Article
Uncontrolled Keywords:	Thyroid, selenium, autoimmunity, antioxidant
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.4 Malattie del sistema emopoietico, linfatico, ghiandolare; Malattie del sistema endocrino
Depositing User:	Matteo Viola
Date Deposited:	17 Jun 2014 13:04
Last Modified:	17 Jun 2014 13:04
URI:	http://eprints.bice.rm.cnr.it/id/eprint/8539

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