Patients with Laron syndrome are protected from development of cancer even if treated with IGF-I

Zvi, Laron and Steuerman, Rachel and Orit, Shevah and Rivka, Kauli (2013) Patients with Laron syndrome are protected from development of cancer even if treated with IGF-I. Reviews in endocrinology and metabolism, 1 (2). pp. 80-82. ISSN 2282-8362

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Abstract

In accordance with the link between increased GH and IGF-I secretion and cancer, we found that homozygous patients with Laron syndrome (severe GH insensitivity) and low to undetectable serum IGF-I are protected from developing cancer even if treated with IGF-I to enhance linear growth.

Item Type:	Article
Uncontrolled Keywords:	Laron syndrome, GH receptor, IGF-I and cancer, GH insensitivity, cancer
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.4 Malattie del sistema emopoietico, linfatico, ghiandolare; Malattie del sistema endocrino
Depositing User:	Matteo Viola
Date Deposited:	17 Jun 2014 13:25
Last Modified:	17 Jun 2014 13:25
URI:	http://eprints.bice.rm.cnr.it/id/eprint/8565

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