Axial CT in the diagnosis of osteoporosis

Guglielmi, Giuseppe and Muscarella, Silvana (2005) Axial CT in the diagnosis of osteoporosis. Clinical cases in mineral and bone metabolism, 2 (2). pp. 110-112. ISSN 1971-3266

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Abstract

Quantitative computed tomography (QCT) is an established technique for measuring bone mineral density (BMD) in the axial spine and appendicular skeleton (forearm, tibia). It provides cross-sectional images, so that it is uniquely able to provide separate estimates of trabecular and cortical bone BMD as well as a true volumetric mineral density in grams per cubic centimeter. However, because of the high responsiveness of spinal trabecular bone and its importance for vertebral strength, it has been principally employed to determine trabecular BMD in the vertebral body. QCT has been used for assessment of vertebral fracture risk, measurement of age-related bone loss, and followup of osteoporosis and other metabolic bone diseases. QCT has a better sensitivity to predict vertebral fracture than projectional methods like DXA, due to its ability to isolate and measure trabecular bone in the center of vertebral body. This mini-review deals with the current capabilities of axial QCT and the recent technical developments, including volumetric acquisition

Item Type:	Article
Uncontrolled Keywords:	Bone Mineral Density (BMD), spinal quantitative computed tomography (QCT), volumetric QCT
Subjects:	600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 616 Malattie (classificare qui la Clinica medica, la medicina basata sull'evidenza, la Medicina interna, la Medicina sperimentale) > 616.7 Malattie del sistema muscoloscheletrico
Depositing User:	Danilo Dezzi
Date Deposited:	24 Apr 2014 11:06
Last Modified:	24 Apr 2014 11:06
URI:	http://eprints.bice.rm.cnr.it/id/eprint/8852

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