Clinical efficacy and Safety of Mimosa tenuiflora Bark Extract in the Rhagades of the Nipple

Mucci, Manuela and Sciocchetti, M. and Benvenuti, Claudio (2006) Clinical efficacy and Safety of Mimosa tenuiflora Bark Extract in the Rhagades of the Nipple. Giornale italiano di ostetricia e ginecologia, 28 (3). p. 106. ISSN 1971-1433

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Abstract

Rhagades of the nipple are an inflammatory disease that, during puerperium, could condition breast-feeding. No specific drug treatments are available so far. A topical preparation mainly based on the extracts of Mimosa tenuiflora bark, having healing and skin regenerating activity, and of Calendula officinalis for its synergistic action. A clinical study was carried out to evaluate the efficacy and safety of this cream formulation in the treatment of breast rhagades in 65 lactating women, mean age 30.6 years, with rhagades of the nipple. The cream was applied at each suckling, 6.3 times a day on average, for 4 weeks. Bleeding rhagades healed in 95.6% of cases within 48-72 hours. Fissures and erythema relieved until their total disappearance and nipple elasticity improved in 81.5% of cases. There was no need to withdraw lactation, except for 3 cases that did not show benefits. Physician’s and mothers’ final judgement on drug efficacy was very good in more than 95% of cases and all the babies manifested their good acceptance. No adverse reactions were complained by the mothers and babies.

Item Type: Article
Subjects: 600 Tecnologia - Scienze applicate > 610 Medicina e salute (Classificare qui la tecnologia dei servizi medici) > 618 Altri rami della medicina; Ginecologia e ostetricia, Pediatria, Geriatria
Depositing User: Matteo Viola
Date Deposited: 03 May 2013 14:16
Last Modified: 16 May 2013 13:13
URI: http://eprints.bice.rm.cnr.it/id/eprint/5118

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